Every package in the Debian repository is an application under this definition.
When I checked out Rails 8, I noticed straight away that not only is there now a new pragmas: block available in the database.yml, but the defaults are now also set to sensible values for a production application. The values provided to my fresh Rails app were equivalent to:
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Cryo-electron microscopy and massively parallel assays shed light on the mechanism by which DICER, a key enzyme in the RNase III family, cleaves RNA at precise locations to produce small RNAs.